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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349260
Species: Homo sapiens
RGD Object: Gene
Symbol: PAFAH1B1
Name: platelet activating factor acetylhydrolase 1b regulatory subunit 1
Acc ID: CHEBI:140618
Term: castor oil
Definition: A mixture of triglycerides obtained by pressing the seeds of the castor oil plant, Ricinus communis. The major component is triricinolein. Typical fatty acid composition on hydrolysis is 87% ricinoleic acid, 7% oleic acid, 3% linoleic acid, 2% palmitic acid, 1% stearic acid, and trace amounts of dihydroxystearic acid.
Chemical ID: MESH:D002368
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PAFAH1B1increases expressionISOPafah1b1 (Rattus norvegicus)6480464CTDCastor Oil results in increased expression of PAFAH1B1 proteinPMID:1354728 PMID:2743081 PMID:8738301
PAFAH1B1multiple interactionsISOPafah1b1 (Rattus norvegicus)6480464CTDisosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]PMID:8738301
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