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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347299
Species: Homo sapiens
RGD Object: Gene
Symbol: SMAD2
Name: SMAD family member 2
Acc ID: CHEBI:35807
Term: N-nitrosodimethylamine
Definition: A nitrosamine that has formula C2H6N2O.
Chemical ID: MESH:D004128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SMAD2increases phosphorylationISOSmad2 (Rattus norvegicus)6480464CTDDimethylnitrosamine results in increased phosphorylation of SMAD2 proteinPMID:14568256
SMAD2multiple interactionsISOSmad2 (Rattus norvegicus)6480464CTDLeu-Ser-Lys-Leu peptide inhibits the reaction [Dimethylnitrosamine results in increased phosphorylation of SMAD2 protein]PMID:14568256
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