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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347299
Species: Homo sapiens
RGD Object: Gene
Symbol: SMAD2
Name: SMAD family member 2
Acc ID: CHEBI:34611
Term: carbofuran
Definition: A 1-benzofuran that has formula C12H15NO3.
Chemical ID: MESH:D002235
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SMAD2increases expressionISOSmad2 (Rattus norvegicus)6480464CTDCarbofuran results in increased expression of SMAD2 mRNAPMID:28982980
SMAD2increases phosphorylationISOSmad2 (Rattus norvegicus)6480464CTDCarbofuran results in increased phosphorylation of SMAD2 proteinPMID:28982980
SMAD2multiple interactionsISOSmad2 (Rattus norvegicus)6480464CTD4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased phosphorylation of SMAD2 protein]PMID:28982980
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