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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346860
Species: Homo sapiens
RGD Object: Gene
Symbol: CDCA8
Name: cell division cycle associated 8
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDCA8increases expressionISOCdca8 (Mus musculus)6480464CTDDiethylnitrosamine results in increased expression of CDCA8 mRNAPMID:17854601
CDCA8multiple interactionsISOCdca8 (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDCA8 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CDCA8 mRNAPMID:18164116 PMID:22129741
CDCA8multiple interactionsISOCdca8 (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDCA8 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA8 mRNA]PMID:17854601 PMID:24535843
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