GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MPO | increases abundance | EXP | | 6480464 | CTD | MPO protein results in increased abundance of Hypochlorous Acid | PMID:35575633 | MPO | increases chemical synthesis | EXP | | 6480464 | CTD | MPO protein results in increased chemical synthesis of Hypochlorous Acid | PMID:34085520 PMID:7772042 | MPO | multiple interactions | EXP | | 6480464 | CTD | 4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [[MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite; [MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Clozapine promotes the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Clozapine promotes the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; Heparin inhibits the reaction [4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; MitoTEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; TEMPOL-H inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid] | PMID:20939553 PMID:34085520 PMID:35575633 PMID:7772042 | | ||||||||||||||||||||||
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