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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346375
Species: Homo sapiens
RGD Object: Gene
Symbol: GSN
Name: gelsolin
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSNdecreases expressionISOGsn (Mus musculus)6480464CTDpirinixic acid results in decreased expression of GSN mRNAPMID:17426115
GSNincreases expressionISOGsn (Mus musculus)6480464CTDpirinixic acid results in increased expression of GSN mRNAPMID:23811191
GSNmultiple interactionsISOGsn (Mus musculus)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GSN mRNAPMID:19710929
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