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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344945
Species: Homo sapiens
RGD Object: Gene
Symbol: LCK
Name: LCK proto-oncogene, Src family tyrosine kinase
Acc ID: CHEBI:75143
Term: N,O-dimethyltyramine
Definition: A secondary amino compound that is tyramine in which the hydrogen of the phenolic hydroxy group has been replaced by a methyl group.
Chemical ID: MESH:D003189
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LCKincreases activityISOLck (Rattus norvegicus)6480464CTDp-Methoxy-N-methylphenethylamine results in increased activity of LCK proteinPMID:27553716
LCKmultiple interactionsISOLck (Rattus norvegicus)6480464CTDatractylon inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased activity of LCK protein]; damnacanthal inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased activity of LCK protein]; pyeongwee-san extract inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased activity of LCK protein]PMID:27553716
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