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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344852
Species: Homo sapiens
RGD Object: Gene
Symbol: GPI
Name: glucose-6-phosphate isomerase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPIaffects expressionEXP 6480464CTDbisphenol A affects the expression of GPI mRNAPMID:30903817
GPIincreases expressionEXP 6480464CTDbisphenol A results in increased expression of GPI proteinPMID:37567409
GPIdecreases expressionISOGpi1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of GPI protein; bisphenol A results in decreased expression of GPI1 mRNAPMID:33221593 PMID:35999755
GPIdecreases expressionISOGpi (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of GPI mRNAPMID:30816183 PMID:32145629 PMID:32528016
GPIincreases expressionISOGpi (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of GPI mRNAPMID:25181051
GPImultiple interactionsISOGpi1 (Mus musculus)6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of GPI1 mRNAPMID:37364641
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