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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344667
Species: Homo sapiens
RGD Object: Gene
Symbol: NRK
Name: Nik related kinase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NRKdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of NRK mRNAPMID:29275510
NRKmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of NRK genePMID:31601247
NRKaffects methylationISONrk (Mus musculus)6480464CTDbisphenol A affects the methylation of NRK promoterPMID:27334623
NRKdecreases expressionISONrk (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of NRK mRNAPMID:25181051
NRKdecreases methylationISONrk (Mus musculus)6480464CTDbisphenol A results in decreased methylation of NRK promoterPMID:27312807
NRKincreases expressionISONrk (Mus musculus)6480464CTDbisphenol A results in increased expression of NRK mRNAPMID:30951980 PMID:34585602
NRKincreases expressionISONrk (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of NRK mRNAPMID:34947998
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