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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343639
Species: Homo sapiens
RGD Object: Gene
Symbol: PTPN1
Name: protein tyrosine phosphatase non-receptor type 1
Acc ID: CHEBI:17440
Term: 4-nitrophenyl phosphate
Definition: An aryl phosphate resulting from the mono-esterification of phosphoric acid with 4-nitrophenol.
Chemical ID: MESH:C008644
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTPN1increases hydrolysisEXP 6480464CTDPTPN1 protein results in increased hydrolysis of nitrophenylphosphatePMID:24287560
PTPN1multiple interactionsEXP 6480464CTDBenzoic Acid analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate]; Thiazolidines analog inhibits the reaction [PTPN1 protein results in increased hydrolysis of nitrophenylphosphate]PMID:24287560
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