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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1331867
Species: Mus musculus
RGD Object: Gene
Symbol: Scd2
Name: stearoyl-Coenzyme A desaturase 2
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scd2affects expressionEXP 6480464CTDPhenobarbital affects the expression of SCD2 mRNAPMID:19136022 PMID:23091169
Scd2increases expressionEXP 6480464CTDPhenobarbital results in increased expression of SCD2 mRNAPMID:19482888
Scd2multiple interactionsEXP 6480464CTDNR1I3 protein affects the reaction [Phenobarbital results in increased expression of SCD2 mRNA]PMID:19482888
Scd2decreases expressionISOSCD (Homo sapiens)6480464CTDPhenobarbital results in decreased expression of SCD1 mRNAPMID:21768169
Scd2increases expressionISOScd2 (Rattus norvegicus)6480464CTDPhenobarbital results in increased expression of SCD2 mRNAPMID:19162173
Scd2increases expressionISOSCD (Homo sapiens)6480464CTDPhenobarbital results in increased expression of SCD mRNAPMID:27180240
Scd2multiple interactionsISOSCD (Homo sapiens)6480464CTD[Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in decreased expression of SCD1 mRNA]; Estradiol inhibits the reaction [Phenobarbital results in decreased expression of SCD1 mRNA]; Progesterone inhibits the reaction [Phenobarbital results in decreased expression of SCD1 mRNA]PMID:21768169
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