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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322702
Species: Mus musculus
RGD Object: Gene
Symbol: Mthfd2
Name: methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mthfd2increases expressionISOMTHFD2 (Homo sapiens)6480464CTDperfluorooctanoic acid results in increased expression of MTHFD2 proteinPMID:26879310
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