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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322470
Species: Mus musculus
RGD Object: Gene
Symbol: Alox12
Name: arachidonate 12-lipoxygenase
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alox12decreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of ALOX12 mRNAPMID:25065748 PMID:31170414
Alox12increases expressionISOALOX12 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of ALOX12 mRNAPMID:28229933 PMID:38568856
Alox12multiple interactionsISOALOX12 (Homo sapiens)6480464CTD[CARM1 mutant form co-treated with sodium arsenite] results in increased expression of ALOX12 mRNA; [PRMT1 mutant form co-treated with sodium arsenite] results in increased expression of ALOX12 mRNAPMID:23699174
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