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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321127
Species: Homo sapiens
RGD Object: Gene
Symbol: ADAM9
Name: ADAM metallopeptidase domain 9
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ADAM9affects expressionEXP 6480464CTDtert-Butylhydroperoxide affects the expression of ADAM9 mRNAPMID:23410634
ADAM9increases expressionEXP 6480464CTDtert-Butylhydroperoxide results in increased expression of ADAM9 mRNAPMID:20847119
ADAM9multiple interactionsEXP 6480464CTD[Rosiglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ADAM9 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ADAM9 mRNA]; Rosiglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ADAM9 mRNA]; Troglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ADAM9 mRNA]PMID:20847119
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