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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319821
Species: Mus musculus
RGD Object: Gene
Symbol: Exo1
Name: exonuclease 1
Acc ID: CHEBI:50223
Term: (+)-dexrazoxane
Definition: A razoxane that has formula C11H16N4O4.
Chemical ID: MESH:D064730
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Exo1multiple interactionsEXP 6480464CTDDexrazoxane inhibits the reaction [Idarubicin results in decreased expression of EXO1 mRNA]; Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of EXO1 protein]PMID:28973540
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