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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319282
Species: Mus musculus
RGD Object: Gene
Symbol: Ppil1
Name: peptidylprolyl isomerase (cyclophilin)-like 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppil1decreases expressionISOPPIL1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PPIL1 proteinPMID:31675489
Ppil1increases expressionISOPpil1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of PPIL1 mRNAPMID:25181051 PMID:32145629
Ppil1increases methylationISOPpil1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of PPIL1 genePMID:28505145
Ppil1multiple interactionsISOPpil1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of PPIL1 mRNAPMID:26496021
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