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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317924
Species: Homo sapiens
RGD Object: Gene
Symbol: PMEPA1
Name: prostate transmembrane protein, androgen induced 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PMEPA1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PMEPA1 mRNAPMID:16474171
PMEPA1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of PMEPA1 genePMID:31601247
PMEPA1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of PMEPA1 genePMID:31601247
PMEPA1affects expressionISOPmepa1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of PMEPA1 mRNAPMID:25181051
PMEPA1decreases methylationISOPmepa1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of PMEPA1 promoterPMID:27312807
PMEPA1increases expressionISOPmepa1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of PMEPA1 mRNAPMID:30816183 PMID:32528016 PMID:34947998
PMEPA1increases expressionISOPmepa1 (Mus musculus)6480464CTDbisphenol A results in increased expression of PMEPA1 mRNAPMID:30951980
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