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GENE - TERM ANNOTATION REPORT

RGD ID: 1317768
Species: Homo sapiens
RGD Object: Gene
Symbol: CUL1
Name: cullin 1
Acc ID: GO:0031146
Term: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
Definition Source(s): PMID:15380083
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CUL1involved_inIEAUniProtKB:Q9WTX6 or ensembl:ENSMUSP00000031697150520179Ensembl GO_REF:0000107
CUL1involved_inIBACGD:CAL0000174561 or MGI:1349658 or PANTHER:PTN000231993 or PomBase:SPAC17G6.12 or SGD:S000002290 or UniProtKB:Q13616150520179GO_Central GO_REF:0000033
CUL1involved_inIDA 150520179UniProt PMID:11961546 PMID:15103331 PMID:22017875 PMID:22017876 PMID:36608670

PMID:11961546 PMID:15103331 PMID:22017875 PMID:22017876 PMID:36608670
CUL1involved_inISSUniProtKB:Q9WTX6150520179UniProt GO_REF:0000024
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