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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316491
Species: Mus musculus
RGD Object: Gene
Symbol: Fbxo21
Name: F-box protein 21
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxo21affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of FBXO21 mRNAPMID:21570461
Fbxo21increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of FBXO21 mRNAPMID:23994337 PMID:25975270
Fbxo21multiple interactionsEXP 6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of FBXO21 mRNAPMID:25975270
Fbxo21decreases expressionISOFbxo21 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of FBXO21 mRNAPMID:21215274 PMID:33387578
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