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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316480
Species: Homo sapiens
RGD Object: Gene
Symbol: PTPN4
Name: protein tyrosine phosphatase non-receptor type 4
Acc ID: CHEBI:79068
Term: crocin-1
Definition: A diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol.
Chemical ID: MESH:C029036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTPN4increases expressionEXP 6480464CTDcrocin results in increased expression of PTPN4 proteinPMID:35085590
PTPN4multiple interactionsEXP 6480464CTDMIR34A mRNA inhibits the reaction [crocin results in increased expression of PTPN4 protein]; PTPN4 protein affects the reaction [crocin results in increased activity of CASP3 protein]PMID:35085590
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