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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316466
Species: Homo sapiens
RGD Object: Gene
Symbol: SRXN1
Name: sulfiredoxin 1
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SRXN1decreases methylationEXP 6480464CTDtert-Butylhydroperoxide results in decreased methylation of SRXN1 genePMID:27509014
SRXN1increases expressionEXP 6480464CTDtert-Butylhydroperoxide results in increased expression of SRXN1 mRNAPMID:23410634 PMID:27509014
SRXN1increases expressionISOSrxn1 (Mus musculus)6480464CTDtert-Butylhydroperoxide results in increased expression of SRXN1 mRNAPMID:22003191
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