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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316327
Species: Mus musculus
RGD Object: Gene
Symbol: Birc6
Name: baculoviral IAP repeat-containing 6
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc6multiple interactionsEXP 6480464CTD[bisphenol A co-treated with LIF protein] results in decreased expression of BIRC6 mRNAPMID:30951980
Birc6affects expressionISOBirc6 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of BIRC6 mRNAPMID:25181051 PMID:30816183 PMID:32145629
Birc6decreases expressionISOBIRC6 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of BIRC6 proteinPMID:31675489
Birc6decreases methylationISOBIRC6 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of BIRC6 genePMID:31601247
Birc6increases expressionISOBirc6 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of BIRC6 mRNAPMID:29097150
Birc6multiple interactionsISOBirc6 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of BIRC6 promoterPMID:23359474
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