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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315457
Species: Homo sapiens
RGD Object: Gene
Symbol: BACH1
Name: BTB domain and CNC homolog 1
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BACH1multiple interactionsEXP 6480464CTD[arsenite results in decreased localization of and results in decreased activity of BACH1 protein] which results in increased expression of HMOX1 protein; arsenite inhibits the reaction [BACH1 protein binds to HMOX1 enhancer]; arsenite inhibits the reaction [BACH1 protein results in decreased expression of HMOX1 protein]; arsenite inhibits the reaction [G3BP1 protein binds to BACH1 mRNA]; arsenite results in decreased localization of and results in decreased activity of BACH1 proteinPMID:18550526 PMID:32406909
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