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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312641
Species: Homo sapiens
RGD Object: Gene
Symbol: IRF2
Name: interferon regulatory factor 2
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IRF2increases expressionISOIrf2 (Mus musculus)6480464CTDGlucose results in increased expression of IRF2 mRNAPMID:34212273
IRF2multiple interactionsISOIrf2 (Mus musculus)6480464CTDHirudins inhibits the reaction [Glucose results in increased expression of IRF2 mRNA]; IRF2 protein affects the reaction [Glucose results in increased expression of and results in increased cleavage of GSDMD protein]; IRF2 protein affects the reaction [Glucose results in increased expression of GSDMD mRNA]PMID:34212273
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