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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311908
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Umps
Name: uridine monophosphate synthetase
Acc ID: CHEBI:88272
Term: azaribine
Definition: A N-glycosyl-1,2,4-triazine that is 6-azauridine acetylated at positions 2', 3' and 5' on the sugar ring. It is a prodrug for 6-azauridine and is used for treatment of psoriasis.
Chemical ID: MESH:C100231
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Umpsincreases activityISOUMPS (Homo sapiens)6480464CTDazaribine results in increased activity of UMPS proteinPMID:1036874
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