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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2r1
Name: cytochrome P450, family 2, subfamily r, polypeptide 1
Acc ID: CHEBI:28177
Term: theophylline
Definition: A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.
Chemical ID: MESH:D013806
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2r1decreases expressionEXP 6480464CTDTheophylline results in decreased expression of CYP2R1 proteinPMID:26851681
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