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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311671
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tcf7l1
Name: transcription factor 7 like 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tcf7l1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TCF7L1 mRNAPMID:25181051
Tcf7l1affects methylationISOTcf7l1 (Mus musculus)6480464CTDbisphenol A affects the methylation of TCF7L1 promoterPMID:27334623
Tcf7l1decreases expressionISOTcf7l1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of TCF7L1 mRNAPMID:25270620
Tcf7l1increases expressionISOTcf7l1 (Mus musculus)6480464CTDbisphenol A results in increased expression of TCF7L1 mRNAPMID:32156529
Tcf7l1increases methylationISOTCF7L1 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of TCF7L1 genePMID:31601247
Tcf7l1multiple interactionsISOTCF7L1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of TCF7L1 genePMID:31601247
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