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GENE - TERM ANNOTATION REPORT

RGD ID: 1310993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tet1
Name: tet methylcytosine dioxygenase 1
Acc ID: GO:0044029
Term: positive regulation of gene expression via chromosomal CpG island demethylation
Definition: An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.
Definition Source(s): PMID:36150101, Wikipedia:Cpg_island
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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