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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310949
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sos1
Name: SOS Ras/Rac guanine nucleotide exchange factor 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sos1decreases expressionEXP 6480464CTDEstradiol results in decreased expression of SOS1 mRNAPMID:32145629
Sos1multiple interactionsEXP 6480464CTD[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of SOS1 mRNAPMID:22465879
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