GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mad2l1 | increases expression | ISO | MAD2L1 (Homo sapiens) | 6480464 | CTD | Camptothecin results in increased expression of MAD2L1 mRNA; Camptothecin results in increased expression of MAD2L1 protein | PMID:30885713 | Mad2l1 | multiple interactions | ISO | MAD2L1 (Homo sapiens) | 6480464 | CTD | Camptothecin promotes the reaction [MAD2L1 protein binds to CDC20 protein]; CDKN1A protein affects the reaction [Camptothecin results in increased expression of MAD2L1 protein]; MAD2L1 protein affects the reaction [Camptothecin results in increased expression of and results in increased activity of CDK1 protein]; MAD2L1 protein affects the reaction [Camptothecin results in increased expression of CASP8 protein]; MAD2L1 protein affects the reaction [Camptothecin results in increased expression of CASP9 protein]; MAD2L1 protein affects the reaction [Camptothecin results in increased expression of CCNB1 protein]; MAPK8 protein affects the reaction [Camptothecin results in increased expression of MAD2L1 protein] | PMID:30885713 | |
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