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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310865
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Krt7
Name: keratin 7
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Krt7decreases expressionISOKRT7 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of KRT7 mRNAPMID:38568856
Krt7increases expressionISOKRT7 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of KRT7 mRNA; sodium arsenite results in increased expression of KRT7 proteinPMID:19524636
Krt7multiple interactionsISOKRT7 (Homo sapiens)6480464CTD[sodium arsenite affects the acetylation of H3-4 protein] which affects the methylation of KRT7 promoterPMID:18448484
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