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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310574
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkacb
Name: protein kinase cAMP-activated catalytic subunit beta
Acc ID: CHEBI:17489
Term: 3',5'-cyclic AMP
Definition: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
Chemical ID: MESH:D000242
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkacbaffects response to substanceISOPRKACB (Homo sapiens)6480464CTDPRKACB protein mutant form affects the susceptibility to Cyclic AMPPMID:29669941
Prkacbmultiple interactionsISOPRKACB (Homo sapiens)6480464CTD[PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PKIA protein]; [PRKACB protein mutant form affects the susceptibility to Cyclic AMP] results in decreased stability of [PRKACB protein mutant form binds to PRKAR1A protein]PMID:29669941
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