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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309793
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Det1
Name: DET1 partner of COP1 E3 ubiquitin ligase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Det1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of DET1 mRNAPMID:25181051
Det1decreases expressionISODET1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of DET1 proteinPMID:33181973
Det1increases expressionISODET1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of DET1 mRNAPMID:25047013
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