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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309397
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sucla2
Name: succinate-CoA ligase ADP-forming subunit beta
Acc ID: CHEBI:50729
Term: mitoxantrone
Definition: A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Chemical ID: MESH:D008942
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sucla2decreases expressionISOSucla2 (Mus musculus)6480464CTDMitoxantrone results in decreased expression of SUCLA2 proteinPMID:34246718
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