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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309388
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Appl1
Name: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appl1decreases expressionISOAPPL1 (Homo sapiens)6480464CTDtert-Butylhydroperoxide results in decreased expression of APPL1 mRNAPMID:15336504
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