GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hipk2 | multiple interactions | EXP | | 6480464 | CTD | Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein] | PMID:28318631 | Hipk2 | multiple interactions | ISO | HIPK2 (Homo sapiens) | 6480464 | CTD | HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; Niclosamide inhibits the reaction [TGFB1 protein promotes the reaction [SMAD3 protein binds to HIPK2 promoter]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein] | PMID:28318631 | Hipk2 | multiple interactions | ISO | Hipk2 (Mus musculus) | 6480464 | CTD | Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 protein] | PMID:28318631 | | ||||||||||||||||||||||
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