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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309306
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mdm4
Name: MDM4 regulator of p53
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdm4multiple interactionsISOMDM4 (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of MDM4 mRNA; [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased expression of MDM4 mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which affects the expression of MDM4 mRNA; [Volatile Organic Compounds co-treated with Ozone] affects the expression of MDM4 mRNAPMID:32699268 PMID:32845096
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