GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfat5 | decreases expression | EXP | | 6480464 | CTD | Sodium Chloride deficiency results in decreased expression of NFAT5 mRNA | PMID:37992803 | Nfat5 | increases expression | EXP | | 6480464 | CTD | Sodium Chloride results in increased expression of NFAT5 mRNA; Sodium Chloride results in increased expression of NFAT5 protein | PMID:37992803 | Nfat5 | multiple interactions | EXP | | 6480464 | CTD | Mannitol inhibits the reaction [Sodium Chloride deficiency results in decreased expression of NFAT5 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in decreased export of FGF23 protein]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of ATP1A1 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of PHEX mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of SGK1 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of SLC8A1 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of SLC9A1 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of SNRK mRNA] | PMID:37992803 | Nfat5 | affects localization | ISO | Nfat5 (Mus musculus) | 6480464 | CTD | Sodium Chloride affects the localization of NFAT5 protein | PMID:20823374 PMID:23867654 | Nfat5 | increases activity | ISO | NFAT5 (Homo sapiens) | 6480464 | CTD | Sodium Chloride results in increased activity of NFAT5 protein | PMID:16303854 | Nfat5 | increases expression | ISO | NFAT5 (Homo sapiens) | 6480464 | CTD | Sodium Chloride results in increased expression of NFAT5 mRNA | PMID:26800359 | Nfat5 | increases expression | ISO | Nfat5 (Mus musculus) | 6480464 | CTD | Sodium Chloride results in increased expression of NFAT5 mRNA; Sodium Chloride results in increased expression of NFAT5 protein | PMID:20823374 PMID:23867654 PMID:37992803 | Nfat5 | multiple interactions | ISO | NFAT5 (Homo sapiens) | 6480464 | CTD | [Sodium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of NFAT5 protein; Apigenin inhibits the reaction [Sodium Chloride results in increased expression of NFAT5 mRNA]; Luteolin inhibits the reaction [Sodium Chloride results in increased expression of NFAT5 mRNA]; myxothiazol inhibits the reaction [Sodium Chloride results in increased activity of NFAT5 protein]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased secretion of FGF2 protein]; Quercetin inhibits the reaction [Sodium Chloride results in increased expression of NFAT5 mRNA]; Rotenone inhibits the reaction [Sodium Chloride results in increased activity of NFAT5 protein] | PMID:16303854 PMID:26800359 | Nfat5 | multiple interactions | ISO | Nfat5 (Mus musculus) | 6480464 | CTD | 2-bromoethylamine inhibits the reaction [Sodium Chloride affects the localization of NFAT5 protein]; 2-bromoethylamine inhibits the reaction [Sodium Chloride results in increased expression of NFAT5 mRNA]; 2-bromoethylamine inhibits the reaction [Sodium Chloride results in increased expression of NFAT5 protein]; Lipopolysaccharides promotes the reaction [Sodium Chloride affects the localization of NFAT5 protein]; Lipopolysaccharides promotes the reaction [Sodium Chloride results in increased expression of NFAT5 mRNA]; Rotenone inhibits the reaction [Sodium Chloride inhibits the reaction [Lipopolysaccharides promotes the reaction [NFAT5 protein binds to IL6 promoter]]]; Sodium Chloride inhibits the reaction [Lipopolysaccharides promotes the reaction [NFAT5 protein binds to IL6 promoter]]; Sodium Chloride promotes the reaction [Lipopolysaccharides affects the localization of NFAT5 protein]; Sodium Chloride promotes the reaction [Lipopolysaccharides results in increased expression of NFAT5 mRNA] | PMID:20823374 PMID:23867654 | | ||||||||||||||||||||||
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