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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ncoa1
Name: nuclear receptor coactivator 1
Acc ID: CHEBI:16422
Term: androst-4-ene-3,17-dione
Definition: A 3-oxo Delta(4)-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.
Chemical ID: MESH:D000735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ncoa1multiple interactionsISONcoa1 (Mus musculus)6480464CTD1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [Androstenedione inhibits the reaction [NR1I3 protein binds to NCOA1 protein]]; Androstenedione inhibits the reaction [NR1I3 protein binds to NCOA1 protein]; isopimpinellin inhibits the reaction [Androstenedione inhibits the reaction [NR1I3 protein binds to NCOA1 protein]]PMID:18692084
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