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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309044
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pnpla2
Name: patatin-like phospholipase domain containing 2
Acc ID: CHEBI:68641
Term: (-)-cotinine
Definition: An N-alkylpyrrolidine that consists of N-methylpyrrolidinone bearing a pyridin-3-yl substituent at position C-5 (the 5S-enantiomer). It is an alkaloid commonly found in Nicotiana tabacum.
Chemical ID: MESH:D003367
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pnpla2multiple interactionsEXP 6480464CTD[Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 mRNA; [Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 proteinPMID:29617909
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