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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308277
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1b10
Name: aldo-keto reductase family 1 member B10
Acc ID: CHEBI:52774
Term: pentane-2,3-dione
Definition: An alpha-diketone that is pentane substituted at the 2- and 3-positions by oxo groups.
Chemical ID: MESH:C013186
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b10increases reductionISOAKR1B10 (Homo sapiens)6480464CTDAKR1B10 protein results in increased reduction of 2,3-pentanedionePMID:23295224
Akr1b10multiple interactionsISOAKR1B10 (Homo sapiens)6480464CTD[AKR1B10 protein results in increased reduction of 2,3-pentanedione] which results in increased chemical synthesis of PentanonesPMID:23295224
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