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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306992
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ercc1
Name: ERCC excision repair 1, endonuclease non-catalytic subunit
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ercc1increases expressionISOERCC1 (Homo sapiens)6480464CTDGlucose results in increased expression of ERCC1 mRNA; Glucose results in increased expression of ERCC1 proteinPMID:22228707
Ercc1multiple interactionsISOERCC1 (Homo sapiens)6480464CTD3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 protein]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 protein]PMID:22228707
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