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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306693
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bach1
Name: BTB domain and CNC homolog 1
Acc ID: CHEBI:78886
Term: 2-tert-butylhydroquinone
Definition: A member of the class of hydroquinones in which one of the ring hydrogens of hydroquinone is replaced by a tert-butyl group.
Chemical ID: MESH:C018855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bach1affects localizationISOBACH1 (Homo sapiens)6480464CTD2-tert-butylhydroquinone affects the localization of BACH1 proteinPMID:28645578
Bach1multiple interactionsISOBACH1 (Homo sapiens)6480464CTD2-tert-butylhydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; [ferric chloride results in increased oxidation of 2-tert-butylhydroquinone] promotes the reaction [2-tert-butylhydroquinone analog binds to BACH1 protein]PMID:28645578
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