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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306665
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tle2
Name: TLE family member 2, transcriptional corepressor
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tle2decreases expressionISOTLE2 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of TLE2 mRNAPMID:26705709
Tle2increases expressionISOTLE2 (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of TLE2 mRNAPMID:20458559
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