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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306076
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ntsr1
Name: neurotensin receptor 1
Acc ID: CHEBI:8058
Term: phencyclidine
Definition: A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.
Chemical ID: MESH:D010622
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ntsr1multiple interactionsISONtsr1 (Mus musculus)6480464CTDNTSR1 gene affects the reaction [Phencyclidine results in decreased expression of DRD1 protein]PMID:20659557
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