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ONTOLOGY REPORT - ANNOTATIONS


Term:phencyclidine
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Accession:CHEBI:8058 term browser browse the term
Definition:A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.
Synonyms:exact_synonym: 1-(1-phenylcyclohexyl)piperidine
 related_synonym: Formula=C17H25N;   InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2;   InChIKey=JTJMJGYZQZDUJJ-UHFFFAOYSA-N;   PCP;   SMILES=C1CCN(CC1)C1(CCCCC1)c1ccccc1;   fenciclidina;   phencyclidinum
 xref: CAS:77-10-1;   DrugBank:DB03575;   Drug_Central:2121;   KEGG:C07575
 xref_mesh: MESH:D010622
 xref: PDBeChem:1PC;   PMID:10379517;   PMID:10696810;   PMID:12206280;   PMID:17265073;   PMID:22467667;   PMID:7250199;   PMID:7968937;   PMID:8103992;   PMID:8855512;   PMID:9007505;   PMID:9786848;   Reaxys:20976544;   Wikipedia:Phencyclidine


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phencyclidine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:6480464
G Ajuba ajuba LIM protein JBrowse link 15 33,208,210 33,218,456 RGD:6480464
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6480464
G Apod apolipoprotein D JBrowse link 11 72,705,204 72,726,263 RGD:6480464
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 JBrowse link X 64,249,576 64,428,444 RGD:6480464
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:6480464
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:6480464
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:6480464
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:6480464
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:6480464
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 JBrowse link 10 67,862,054 67,863,255 RGD:6480464
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase JBrowse link 10 88,490,798 88,497,357 RGD:6480464
G Cplx2 complexin 2 JBrowse link 17 10,756,871 10,828,811 RGD:6480464
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 JBrowse link 12 18,679,809 18,709,397 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 JBrowse link 17 84,986,994 85,141,464 RGD:6480464
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Fdft1 farnesyl diphosphate farnesyl transferase 1 JBrowse link 15 46,339,248 46,367,302 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 80,214,691 80,221,417 RGD:6480464
G Foxp2 forkhead box P2 JBrowse link 4 41,364,441 41,944,685 RGD:6480464
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 JBrowse link 20 1,955,344 1,984,907 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Gcc1 GRIP and coiled-coil domain containing 1 JBrowse link 4 55,708,040 55,719,884 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 JBrowse link 8 1,548,145 2,045,874 RGD:6480464
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:6480464
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hoxb9 homeo box B9 JBrowse link 10 84,119,772 84,124,963 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Jund JunD proto-oncogene, AP-1 transcription factor subunit JBrowse link 16 20,485,028 20,486,707 RGD:6480464
G Kcnh1 potassium voltage-gated channel subfamily H member 1 JBrowse link 13 110,920,712 111,232,291 RGD:6480464
G Kcnip3 potassium voltage-gated channel interacting protein 3 JBrowse link 3 120,023,062 120,087,650 RGD:6480464
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 JBrowse link 7 120,717,378 120,744,602 RGD:6480464
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G LOC100911804 apolipoprotein L3-like JBrowse link 7 118,979,230 118,986,699 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:6480464
G Mal mal, T-cell differentiation protein JBrowse link 3 120,209,647 120,233,655 RGD:6480464
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:6480464
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 3 81,295,023 81,304,181 RGD:6480464
G Mbp myelin basic protein JBrowse link 18 79,326,738 79,437,310 RGD:6480464
G Mobp myelin-associated oligodendrocyte basic protein JBrowse link 8 128,824,420 128,854,492 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:6480464
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 3 43,111,258 43,128,391 RGD:6480464
G Ntsr1 neurotensin receptor 1 JBrowse link 3 175,982,313 176,046,345 RGD:6480464
G P2ry1 purinergic receptor P2Y1 JBrowse link 2 151,314,818 151,320,312 RGD:6480464
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:6480464
G Plp1 proteolipid protein 1 JBrowse link X 107,494,326 107,511,355 RGD:6480464
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:6480464
G Prkcg protein kinase C, gamma JBrowse link 1 64,407,098 64,433,698 RGD:6480464
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:6480464
G Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein JBrowse link 1 219,403,970 219,406,129 RGD:6480464
G Pvalb parvalbumin JBrowse link 7 119,428,657 119,443,674 RGD:6480464
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:6480464
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:6480464
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:6480464
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:6480464
G Selplg selectin P ligand JBrowse link 12 48,577,905 48,579,196 RGD:6480464
G Sema3b semaphorin 3B JBrowse link 8 116,353,791 116,362,655 RGD:6480464
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:6480464
G Slc17a6 solute carrier family 17 member 6 JBrowse link 1 106,980,463 107,038,717 RGD:6480464
G Smad5 SMAD family member 5 JBrowse link 17 8,307,448 8,336,996 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:6480464
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:6480464
G Syn2 synapsin II JBrowse link 4 147,037,179 147,195,096 RGD:6480464
G Syt2 synaptotagmin 2 JBrowse link 13 51,569,248 51,577,824 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464
G Tead4 TEA domain transcription factor 4 JBrowse link 4 161,542,566 161,619,848 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:6480464
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta JBrowse link 3 160,391,108 160,399,931 RGD:6480464
G Zrsr1 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1 JBrowse link 14 107,750,162 107,751,895 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      chemical role 19251
        base 16715
          piperidine 100
            phencyclidine 89
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19398
                        hydrogen molecular entity 19388
                          hydrides 18363
                            inorganic hydride 17213
                              pnictogen hydride 17176
                                nitrogen hydride 17011
                                  azane 16704
                                    ammonia 16703
                                      organic amino compound 16702
                                        secondary amino compound 6473
                                          secondary amine 1658
                                            piperidine 100
                                              phencyclidine 89
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.