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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306026
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Msrb2
Name: methionine sulfoxide reductase B2
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Msrb2decreases expressionISOMSRB2 (Homo sapiens)6480464CTDtert-Butylhydroperoxide results in decreased expression of MSRB2 proteinPMID:38272317
Msrb2decreases response to substanceISOMSRB2 (Homo sapiens)6480464CTDMSRB2 protein results in decreased susceptibility to tert-ButylhydroperoxidePMID:15914630
Msrb2multiple interactionsISOMSRB2 (Homo sapiens)6480464CTDCurcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of MSRB2 protein]; salvianolic acid B inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of MSRB2 protein]PMID:38272317
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