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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305904
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Epyc
Name: epiphycan
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epycincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of EPYC mRNAPMID:32109520
Epycdecreases expressionISOEPYC (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of EPYC mRNAPMID:11007951
Epycincreases expressionISOEpyc (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of EPYC mRNAPMID:15328365 PMID:16611356 PMID:19933214
Epycmultiple interactionsISOEPYC (Homo sapiens)6480464CTDCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of EPYC mRNA]PMID:11007951
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