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GENE - TERM ANNOTATION REPORT

RGD ID: 1305467
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prpf8
Name: pre-mRNA processing factor 8
Acc ID: GO:0071005
Term: U2-type precatalytic spliceosome
Definition: A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.
Definition Source(s): GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prpf8part_ofISOPRPF8 (Homo sapiens)1624291RGD PMID:28781166 PMID:29361316 PMID:30315277

PMID:28781166 PMID:29361316 PMID:30315277
Prpf8part_ofIEAUniProtKB:Q6P2Q9 or ensembl:ENSP000003043501600115EnsemblGO_REF:0000107

GO_REF:0000107
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