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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304884
Species: Rattus norvegicus
RGD Object: Gene
Symbol: 6430548M08Rikl
Name: RIKEN cDNA 6430548M08 gene like
Acc ID: CHEBI:17823
Term: calcitriol
Definition: A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.
Chemical ID: MESH:D002117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
6430548M08Rikldecreases expressionISOKIAA0513 (Homo sapiens)6480464CTDCalcitriol results in decreased expression of KIAA0513 mRNAPMID:26485663
6430548M08Riklincreases expressionISOKIAA0513 (Homo sapiens)6480464CTDCalcitriol results in increased expression of KIAA0513 mRNAPMID:21592394
6430548M08Riklmultiple interactionsISOKIAA0513 (Homo sapiens)6480464CTD[Testosterone co-treated with Calcitriol] results in increased expression of KIAA0513 mRNAPMID:21592394
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